Management Team

Donna L. Tempel, Ph.D., M.B.A.

President, Chief Executive Officer and co-founder of Prothex, Inc.

Dr. Tempel is founder, President and CEO overseeing all of Prothex’s business, contributing notable strength in the areas of strategy, finance, partnership and business development.

Prior to founding Prothex, Dr. Tempel was CEO of Drais Pharmaceuticals and Chief Operating Officer of AkaRx, Inc. a privately held company that was sold to Eisai in January of 2010. Earlier in her career, she was Vice President, Project Management at Yamanouchi Pharma America and has held various positions in Clinical Research and Development at Bristol Myers Squibb and Johnson and Johnson.

Dr. Tempel received a B.S. degree in Psychology and Mathematics from Hunter College, CUNY, an MBA in Finance from Farleigh Dickinson University, and a Ph.D. in Neurological Sciences from CUNY/Mount Sinai School of Medicine.

James A. Bianco, M.D.

Chief Development Officer

Dr. Bianco joined Prothex in 2018 and is a driving force for Prothex in identifying, acquiring, funding, and developing our pipeline compounds.

Dr. Bianco’s medical and entrepreneurial background bring great value. He was principal founder and CEO of CTI Biopharma and has more than 25 years of experience in building biotech/bio-pharmaceutical businesses. He has hands-on operational experience covering all aspects of drug development, manufacturing, financing, licensing and M&A.

Jim earned his M.D from the Mount Sinai Icahn School of Medicine and completed his residency and chief residency at the Mount Sinai Medical Center in NYC. He completed his fellowship in Hematology/Oncology at the University of Washington/Fred Hutchinson Cancer Research Center and was Assistant Professor of Medicine and Director of the Bone Marrow Transplant Unit at a “Hutch” affiliate (SVAMC).

Robert M. Schinagl, Ph.D.

Chief Operating Officer

Dr. Schinagl is a founding employee of Prothex and provides central and integrated support for Prothex’s development operations and many business functions, with focus on resourcing development activities, managing contractors, and delivering on time.

Prior to Prothex, Rob was VP of Project Management for Drais Pharmaceuticals and held various positions in Project, Portfolio and Alliance Management at ImClone Systems and Eli Lilly. With more than 25 years of Bio/Pharma experience, he’s served in various research and development roles at companies such as Yamanouchi Pharma America, Quintiles, Osiris Therapeutics, and Electro-Biology, Inc.

Dr. Schinagl earned his B.S.E. in biomedical engineering at the University of Pennsylvania and M.S.E. and Ph.D. in bioengineering at the University of California, San Diego.

Christopher S. Del Mastro

Vice President, Finance and Administration

Mr. Del Mastro is a founding employee of Prothex and is our key player in the management of corporate finance, accounting and operations, as well as negotiating and maintaining contracts with all of the company’s external resources.

Prior to assuming this role at Prothex, Chris was Sr. Director of Finance and Contracts for Drais Pharmaceuticals and Associate Director to Operations at AkaRx, Inc. Across his 20+ years in the industry, he previously held various positions in clinical operations at Yamanouchi Pharma America Inc. and Novartis Pharmaceuticals.

Mr. Del Mastro holds a B.A. degree from Montclair State University.